Rep. Alexandria Ocasio-Cortez on Sunday urged President Joe Biden against being “limited by Republicans” in moving infrastructure legislation forward, calling the political moment “our one big shot” on issues from Medicare to the climate emergency.

The New York Democrat’s remarks in an interview with NBC‘s “Meet the Press” came a day after Biden walked back his vow of a two-track approach to infrastructure in which, to progressive praise and GOP ire, he would sign a $579 billion bipartisan deal if it came with a separate Democratic reconciliation bill “in tandem.”

While Democrats can “welcome collaboration with Republicans and in those areas where this is agreement,” said Ocasio-Cortez, “Republicans are more than welcome to join so that we can get this work on infrastructure done.”

“But that doesn’t mean that the president should be limited by Republicans,” she said, “particularly when we have a House majority, we have 50 Democratic senators, and we have…

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